Skin · Aesthetic
Polynucleotide Skin Rejuvenation
Next-generation injectable skin regeneration. Polynucleotides repair, hydrate, and rebuild skin at a cellular level for lasting improvement in quality, tone, and firmness.
Book this treatment
No-obligation consultation.
Overview
Genuine skin regeneration from within
Polynucleotides (PNs) are a cutting-edge injectable treatment that works at a cellular level to regenerate and repair the skin. Derived from highly purified salmon or trout DNA, polynucleotides stimulate fibroblast activity, the cells responsible for producing collagen, elastin, and hyaluronic acid, triggering genuine skin regeneration from within.
Unlike skin boosters that simply hydrate the skin, polynucleotides actively repair damaged tissue, improve skin structure, and restore long-term skin quality. They are particularly effective for delicate areas such as the under-eyes, where other treatments can be limited, and for patients who want to genuinely improve their skin health rather than mask signs of ageing.
Popular brands used at Radiant Health Clinic include Plinest, Lumi Eyes, and Nucleofill. Your practitioner will recommend the most appropriate formulation at consultation.
- Genuine skin regeneration at a cellular level
- Reduces dark circles and hollowness under the eyes
- Improves skin firmness, elasticity, and texture
- Stimulates collagen and elastin production
- Long-lasting results that improve over time
- Suitable for delicate areas including under-eyes
Areas we treat
Where polynucleotides work
Versatile across the face and beyond, each area assessed individually at your consultation.
The tear trough area, where dark circles and hollowness are improved without adding volume.
Full-face rejuvenation to improve skin quality, tone, and firmness.
Restores firmness and texture to crêpey or ageing skin.
Smooths and rejuvenates the chest area.
Improves skin quality and texture on the backs of the hands.
Every area we treat
How it works
How it works
Consultation
Your skin is assessed, your concerns discussed, and the most appropriate polynucleotide formulation recommended.
Preparation
The treatment area is cleansed. Topical anaesthetic can be applied on request.
Injection
Small amounts of polynucleotides are injected into the targeted area using very fine needles.
Post-treatment
The area is gently cleansed. Mild bumps at injection sites are normal and resolve quickly.
Your safety
Suitability & aftercare
A medical treatment, delivered to medical standards. Here’s who it suits, and how to care for your skin afterwards.
Is it right for you?
Adults looking to improve skin quality, reduce dark circles, improve fine lines and laxity, or achieve long-term skin regeneration. Particularly suitable for those who have not achieved the desired results from other treatments.
Please tell us at consultation
Not suitable during pregnancy or breastfeeding. Not recommended for patients with a known allergy to fish or fish products, as polynucleotides are fish-derived. Not suitable over active skin infections. A full medical assessment is carried out at your consultation.
Caring for your results
Real results
Before & after
Amazing knowledge with a wealth of experience. Safe to know I'm in the hands of ladies who are medically trained and advanced nurse practitioners. I wouldn't trust anyone else other than Kayte and Anna.
Verified patient
Polynucleotide Skin Rejuvenation pricing
The specific polynucleotide product used will be confirmed at consultation based on your skin concerns and the area being treated.
No pressure, ever
Interested in polynucleotide skin rejuvenation?
Book a consultation and our practitioners will assess your skin and recommend the right regeneration plan for you.
Your clinician
Treated by Kayte
Kayte is an Advanced Nurse Practitioner and Independent Prescriber who leads the clinic’s aesthetic injectable and skin-health work, with a meticulous, natural-first approach.
Every treatment at Radiant Health is carried out by a qualified clinician, in a CQC-registered clinic, with your safety and natural-looking results always coming first.
Still deciding?
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Common questions
Common questions
What is the difference between polynucleotides and Profhilo?
Both are injectable skin quality treatments, but they work differently. Profhilo is a high-concentration hyaluronic acid that bio-remodels the skin and provides intense hydration. Polynucleotides work at a cellular level to actively regenerate skin tissue by stimulating fibroblasts. They can also be used together for complementary results.
Are polynucleotides suitable for under-eye treatment?
Yes, polynucleotides are particularly well suited to the delicate under-eye area. They help reduce dark circles, improve skin texture, and address hollowness without adding volume or looking unnatural.
How long before I see results?
Results develop gradually over 4–8 weeks as skin regeneration occurs. Optimal results are seen after completing a full course of three sessions.
Is the treatment painful?
Most patients tolerate the treatment very well. The needles used are very fine. Topical anaesthetic is available on request.
Who are polynucleotides suitable for?
Polynucleotides are suitable for a wide range of patients, from those in their late twenties noticing early skin changes, to more mature skin requiring genuine regeneration. Your practitioner will advise at consultation.
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